Test Name: Cotinine (COT) Urine Clinical Utility: The Cotinine test is used to detect exposure to nicotine and tobacco products by measuring cotinine, a primary metabolite of nicotine. Cotinine Single vaping episode of cannabis could yield positive results in urine drug tests Vaping and Smoking (Nicotine) Rapid Test Rezure Health The Real Consequences of Failing a Drug Test After Vaping Can Vaping Show Up on a Drug Test?