What is glutathione and why must we protect patient access to it? Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Frontiers Glutathione deficiency in the pathogenesis of SARS CoV 2 infection and its effects upon the host immune response in severe COVID 19 disease Glutathione: Role in Oxidative Nitrosative Stress, Antioxidant Defense, and Treatments Raj Rai 2021 ChemistrySelect Wiley Online Library JCI Glutathione peroxidase potentiates the inhibition of platelet function by S nitrosothiols.