Frontiers Targeting the initiator to activate both ferroptosis and cuproptosis for breast cancer treatment: progress and possibility for clinical application An integrative multi omics analysis leveraging Mendelian randomization and subsequent experimental validation prioritizes glutathione S transferase mu 5 (GSTM5) as a genomic stability related gene and a therapeutic vulnerability to PLK1 inhibition in New research targeting senescent zombie" cells highlights potential #cancer therapies reducing inflammation, tumor growth, and treatment related damage through Glutathione Peroxidase 4 (GPX4) inhibition. . Article Frontiers The Metabolic Mechanisms of Breast Cancer Metastasis Glutathione Dependent Pathways in Cancer Cells