Melanosis Coli Gastroenterology & Hepatology of CNY PT 141 Nasal Spray: The Breakthrough Peptide for Intimacy, Energy, and Vitality Your Health Magazine Melanosis Coli El Atlas Gastrointestinal gastrointestinalatlas.com Photomicrograph of an endoscopic colon biopsy (colonoscopy) showing melanosis coli, an accumulation of brown pigment (lipofuscin) within macrophages of the colonic mucosa, related to use of laxatives. Stock Photo Adobe Stock During colonoscopy, your gastroenterologist can tell if you abuse stimulant or herbal laxatives, especially those that contain senna. The condition is called melanosis coli or black colon. The frequent use of stimulant